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Lars Bode, PhD

Professor
Division of Neonatology and Division of Gastroenterology, Hepatology, and Nutrition
Department of Pediatrics
Chair of Collaborative Human Milk Research
Director, Human Milk Institute (HMI)
Director, Larsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence (MOMI CORE)
UC San Diego 

 

Areas of Expertise: Breastfeeding Safety, Human Milk Biology, Human Milk Antimicrobials

Dr. Bode’s laboratory focuses on human milk oligosaccharides (HMOs), a group of complex sugar molecules that represent the third most abundant component of human milk after lactose and lipids. The goal of Dr. Bode’s research is to understand how HMOs are synthesized in the human mammary gland and how they benefit the breast-fed infant and potentially also the breastfeeding mother. The laboratory employs a multidisciplinary collaborative research approach that combines preclinical studies and human cohort and intervention studies with the goal to identify structure-function relationships in a variety of clinical contexts related to maternal and infant health. The team has developed tools for rapid high-throughput HMO composition analysis and collaborates with partners from around the world to identify maternal ctors that influence HMO composition and to link HMO composition to infant health and disease outcomes.

Today, as Director of MOMI CORE, Dr. Bode dedicates his research excellence, leadership and partnership building skills to accelerate and effectively translate human milk research into improved maternal and infant health, globally.

Lackey KA, Pace RM, Williams JE, Bode L, Donovan SM, Järvinen KM, Seppo AE, Raiten DJ, Meehan CL, McGuire MA, McGuire MK (2020) SARS-CoV-2 and human milk: what is the evidence? Maternal & Child Nutrition 16(4):e13032 [https://pubmed.ncbi.nlm.nih.gov/32472745/]

Chambers CD, Krogstad P, Bertrand K, Contreras D, Tobin NH, Bode L, Aldrovandi GM (2020) Evaluation of SARS-CoV-2 in Breastmilk from 18 Infected Women. JAMA 324(13):1347-1348 [https://pubmed.ncbi.nlm.nih.gov/32822495/]

Spatz DL, Davanzo R, Mueller JA, Powell R, Rigourd V, Yates A, Geddes D, van Goudoever JB, Bode L (2020) Promoting and Protecting Human Milk & Breastfeeding in a COVID-19 World. Frontiers in Pediatrics 8:633700 [https://pubmed.ncbi.nlm.nih.gov/33614547/]

Merewood A, Bode L, Davanzo R, Perez-Escamilla R (2021) Breastfeed or be vaccinated – An unreasonable recommendation. Lancet 397(10274):578 [https://pubmed.ncbi.nlm.nih.gov/33549167/]

Krogstad P, Contreras D, Ng H, Tobin NH, Chambers CD, Bertrand K, Bode L, Aldrovandi GM (2021) No Infectious SARS-CoV-2 in Breast Milk From a Cohort of 110 Lactating Women. Pediatric Research 2022;doi10.1038/s41390-021-01902-y (ahead of print) [https://pubmed.ncbi.nlm.nih.gov/35042956/]

Bode L, Raman AS, Murch SH, Rollins NC, Gordon JI (2020) Understanding the mother-breastmilk-infant "triad". Science 367(6482):1070-1072. [https://www.science.org/doi/10.1126/science.aaw6147]